COMPARISON OF ANTIOXIDANT AND ANTI-INFLAMMATORY EFFECTS OF SOME POLYPHENOLIC COMPOUNDS AND ITS BIOTRANSFORMATION EXTRACTS

Objective: Microbial transformations are green biotechnological processes where different microorganisms, or their enzymes used to produce new metabolites from defined substrates. Hesperidin, quercetin, and derivatives have been proven in scientific research a variety of biological activities such as antioxidant, antimicrobial, anticancer activities. 
 Material Method: transformation hesperidin quercetin was carried out utilizing 13 microbial strains this study. The extracts were investigated antioxidant (DPPH· ABTS·+ methods) anti-inflammatory effects.
 Result Discussion: biotransformation is observed 5 strains. There Rhizopus stolonifera, Saccharomyces pararoseus, S. cerevisiae, Penicillium claviforme, Fusarium solani while identified Aspergillus flavus claviforme. results show that the obtained with more effective terms effects. by strain has not researched previously.